Charles Louis Davis and Samuel Wesley Thompson DVM Foundation
For the Advancement of Veterinary and Comparative Pathology
info@cldavis.org | Phone: 847-367-4359 | Fax: 847-247-1869
Learn all about gross lesions in domestic, laboratory, and exotic animals.
Recognize and interpret conditions which may affect experimental results or alter the health of laboratory animals.
Learn about glomerular pathology, glomerular ultrastructure, and pathology of tubulointerstitial disease.
The theme of this year is fungal diseases.
Dr. Donal O'Toole (second from left) is demonstrating lesions, and Dr. Melissa Macias (second from right) is translating into Spanish at the 10th seminar of the Argentinean Division of the Foundation.
Participants of the 4th Chilean Seminar of the Foundation on the campus of the University of Chile in Santiago de Chile in August 2016.
The European Symposium of the Foundation was held in Bologna, Italy, in September 2016.
Janssen R&D (J&J Pharmaceuticals) and the Davis-Thompson sponsored and hosted the Northeast Day Seminar at Spring House, Pennsylvania in September 2016.
We are currently having problems with our bookstore, and we are sorry for the inconvenience. Please call the Main Office at 847-367-4359 to place all orders, and they will be shipped immediately. This problem should be resolved within the month.
The Foundation is proud to make Noah's Arkive, a searchable
collection of veterinary pathology images, available online at
no cost. Special thanks to the University of Georgia for transferring
the database and image collection to the Foundation!
The main goal of these Diagnostic Exercises is to provide interesting cases, focusing on the gross pathological lesions and associated histopathologic or cytologic findings. This material can be of great use for veterinary students, in-training pathologists, and ACVP diplomates alike.
There will be one contribution per month of the year; anyone may contribute. To do so, please contact Dr. Vinicius Carreira at vinicius.carreira@gmail.com to identify a convenient date for your submission and to receive templates to be used. Spots will be filled out on a first-come first-served basis.
| Exercise | Thumbnail | Answer |
|---|---|---|
| Click here for case history |  |
Click here for case synopsis |
New today in Noah - from the archives of the Armed Forces Institute of Pathology.
Tissue from a sea lion pup.
Morphologic diagnosis: Severe bilateral hyphema.
Cause: Leptospira pomona
Comment: Periodic outbreaks of Leptospira pomona occur in California sea lions. In addition to characteristic renal lesions, it may result in reproductive failure, abortions and still borns. Affected pups have extensive subcutaneous hemorrhage as well as hyphen, which has resulted in the term, "red eye" for this disease.
New today in Noah - again from Fabrizio Grandi - he is on a hot streak!
Tissue from a dog.
Morphologic diagnosis: MULTIFOCAL TO COALESCING XANTHOGRANULOMATOUS GLOSSITIS; CANINE ATYPICAL MUCOSA-ASSOCIATED XANTHOMAS.
9 YEARS-OLD SHI-TZU DOG. Canine atypical mucosa-associated xanthoma is a rare or underdiagnosed disorder characterized by solitary to multiple papillary nodules or raised plaques located on dorsal or ventral surface of the tongue. Microscopically, these lesions are characterized by the presence of clusters of large, vacuolated, lipid-laden macrophages covered by a hyperplastic, hyperkeratotic, squamous epithelium. In dogs, xanthomas can be associated with hyperlipidemia, diabetes mellitus, hypothyroidism, and hyperadrenocorticism.
References 1. Balme E. et al. Multiple atypical mucosal xanthomas in a dog similar to human verruciform xanthoma. J Vet Diagn Invest 21:124–128 (2009).
New in Noah from the archives of the Armed Forces Institute of Pathology.
Tissue from a duck.
Name an associated condition: Zinc toxicosis
Name an associated lesion: Pancreatic necrosis
Comment: From a eider duck - original image from the National Zoo. This coin was likely tossed in an exhibit for "good luck", but was not good luck for this duck that ingested it.
Pennies are primarily composed of zinc, with only a thin patina of copper. Affected animals may demonstrate pancreatic necrosis, renal tubular necrosis, and or hemolytic anemia resulting from the leaching of zinc from pennies in the acidic pH of the stomach.
Pancreatic necrosis is the classic lesion associated with zinc toxicosis, as the pancreas stores significant amounts of zinc and is actually involved in zinc metabolism. But too much overwhelms cellular metallothioneins, resulting in oxidative stress. Another theory of cellular damage postulates that free zinc may actually activate trypsinogen.
Either way, keep your pennies in your pockets!
I will be speaking at RTC@ACT on November 4 about Tg.rasH2 model. If you are attending please join me.
Bruce Williams shared a link to the group: C.L. Davis and S.W. Thompson DVM Foundation.
Don't miss the 17th annual DTF/AAVLD Diagnostic Pathology meeting -registration is open and seats are limited!
The Davis-Thompson DVM Foundation will be conducting an eight-hour continuing education symposium entitled "Diagnostic Renal Pathology" . Course Director: Paco Uzal (University of California Davis) and invited guest lecturer Rachel Cianciolo (Ohio State University). Topics include: normal histology and ultra-structure of the kidney with a review of the nephron physiology and pathophysiology, glomerular diseases in small and large animals, anomalies of development including hereditary nephropathies, whole organ renal diseases, tubulointerstitial diseases, neoplastic diseases of the kidney and discussion of the presented material. Didactic lectures will be combined with audience participation to result in a engrossing day-long seminar. Don't miss out on what promises to be another exciting Davis-Thompson/AAVLD co-sponsered symposium.
Tuition of $150 includes refreshments, pdfs of presentations and continuing education credits. The tuition fee will be waived for the winners of the travel award. You must Register to quarantee receipt of materials. Registeration is through Davis/Thompson Foundation and is separate from AAVLD meeting registration.
17th Davis/Thompson Diagnostic Pathology Symposium: Diagnostic Renal Pathology
regonline.com
The Davis-Thompson DVM Foundation will be conducting an eight-hour continuing education symposium entitled "Diagnostic Renal Pathology" . Course Director: Paco Uzal (Universit
